Digestive system ppt. VI

The Liver
?Is wrapped in tough fibrous capsule
?Is covered by visceral peritoneum
?Is divided into lobes
The Liver
?Histological Organization of the Liver
?Liver lobules:
?The basic functional units of the liver
?Each lobe is divided:
?by connective tissue
?into about 100,000 liver lobules
?about 1 mm diameter each
?Is hexagonal in cross section
?With six portal areas(hepatic triads):
?one at each corner of lobule
The Liver
?Hepatocytes
?Are liver cells
?Adjust circulating levels of nutrients:
?Through selective absorption and secretionThe Gallbladder
?Is a pear-shaped, muscular sac
?Stores and concentrates bile prior to excretion into small intestine
?Is located in the fossaon the posterior surface of the liver’s right lobe
?In a liver lobule form a series of irregular plates arranged like wheel spokes
?Many Kupffercells (stellatereticuloendothelialcells) are located in sinusoidal lining
?As blood flows through sinusoids:
?Hepatocytesabsorb solutes from plasma
?And secrete materials such as plasma proteinsThe Liver
The Physiology of the Liver
1.Metabolic regulation
2.Hematological regulation
3.Bile production